One of the features I thought was lost in Visual Studio 2005, directory/file based searches, is not!
When you bring up Files In Files (Ctrl+Shift+F, Edit.FindinFiles) you can type in the path straight

Or you can click on the Epsilon button at the side and select many directories.

Look you can even have named sets.
I take back all those bad word I said about you Microsoft. Well maybe I leave some the table, because it has taken me so long to re-find one of my favorite features.